Which description best differentiates TRALI from TACO?

Which description best differentiates TRALI from TACO?

• A. TRALI is cardiogenic edema; TACO is noncardiogenic edema.
• B. TRALI is noncardiogenic edema with hypoxemia; TACO is cardiogenic edema; treat with oxygen and diuretics for TACO; supportive care for TRALI and contact transfusion service.
• C. TRALI presents with hypertension only; TACO with hypotension.
• D. TRALI responds to diuretics; TACO requires nothing.

Answer: (B)

Distinguish the two transfusion-related lung injuries by the nature of the edema and the approach to treatment. TRALI is noncardiogenic pulmonary edema caused by increased capillary permeability, leading to hypoxemia after transfusion; management is supportive—oxygen, ventilation as needed, stopping the transfusion and notifying the transfusion service. TACO is cardiogenic edema from volume overload, a pressure-related edema; it commonly presents with signs of fluid overload and hypertension, and it responds to diuretics and careful fluid management. The described option correctly states that TRALI is noncardiogenic edema with hypoxemia, TACO is cardiogenic edema, treats TACO with oxygen and diuretics, and uses supportive care for TRALI plus contacting the transfusion service.

Distinguish the two transfusion-related lung injuries by the nature of the edema and the approach to treatment. TRALI is noncardiogenic pulmonary edema caused by increased capillary permeability, leading to hypoxemia after transfusion; management is supportive—oxygen, ventilation as needed, stopping the transfusion and notifying the transfusion service. TACO is cardiogenic edema from volume overload, a pressure-related edema; it commonly presents with signs of fluid overload and hypertension, and it responds to diuretics and careful fluid management. The described option correctly states that TRALI is noncardiogenic edema with hypoxemia, TACO is cardiogenic edema, treats TACO with oxygen and diuretics, and uses supportive care for TRALI plus contacting the transfusion service.